Search on: GLUCAGON-LIKE PEPTIDE 1 
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Descriptor English:   Glucagon-Like Peptide 1 
Descriptor Spanish:   Péptido 1 Similar al Glucagón 
Descriptor Portuguese:   Peptídeo 1 Semelhante ao Glucagon 
Synonyms English:   GLP 1
GLP-1
Glucagon Like Peptide 1
Glucagon-Like Peptide-1  
Tree Number:   D06.472.317.680.500.500
Definition English:   A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake. 
Pharmacological Action:   Incretins
 
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   50567 
Unique Identifier:   D052216 

Occurrence in VHL:
 

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